Bottom-Up Assembly of Silica and Bioactive Glass Supraparticles with Tunable Hierarchical Porosity

Journal article
(Original article)


Publication Details

Author(s): Egly S, Fröhlich C, Vogel S, Grünewald A, Wang J, Detsch R, Boccaccini AR, Vogel N
Journal: Langmuir
Publisher: American Chemical Society
Publication year: 2018
Volume: 34
Journal issue: 5
Pages range: 2063-2072
ISSN: 0743-7463
eISSN: 1520-5827


Abstract

We investigate the formation of spherical supraparticles with controlled and tunable porosity on the nanometer and micrometer scales using the self-organization of a binary mixture of small (nanometer scale) oxidic particles with large (micrometer scale) polystyrene particles in the confinement of an emulsion droplet. The external confinement determines the final, spherical structure of the hybrid assembly, while the small particles form the matrix material. The large particles act as templating porogens to create micropores after combustion at elevated temperatures. We control the pore sizes on the micrometer scale by varying the size of the coassembled polystyrene microspheres and produce supraparticles from both silica- and calcium-containing CaO/SiO2 particles. Although porous supraparticles are obtained in both cases, we found that the presence of calcium ions substantially complicated the fabrication process since the increased ionic strength of the dispersion compromises the colloidal stability during the assembly process. We minimized these stability issues via the addition of a steric stabilizing agent and by mixing bioactive and silica colloidal particles. We investigated the interaction of the porous particles with bone marrow stromal cells and found an increase in cell attachment with increasing pore size of the self-assembled supraparticles.


FAU Authors / FAU Editors

Boccaccini, Aldo R. Prof. Dr.-Ing.
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Detsch, Rainer Dr.-Ing.
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Egly, Steffen
Lehrstuhl für Feststoff- und Grenzflächenverfahrenstechnik
Fröhlich, Christina
Lehrstuhl für Feststoff- und Grenzflächenverfahrenstechnik
Grünewald, Alina
Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)
Vogel, Nicolas Prof. Dr.
Professur für Partikelsynthese
Wang, Junwei
Lehrstuhl für Feststoff- und Grenzflächenverfahrenstechnik


Additional Organisation
Exzellenz-Cluster Engineering of Advanced Materials


Research Fields

A1 Functional Particle Systems
Exzellenz-Cluster Engineering of Advanced Materials


How to cite

APA:
Egly, S., Fröhlich, C., Vogel, S., Grünewald, A., Wang, J., Detsch, R.,... Vogel, N. (2018). Bottom-Up Assembly of Silica and Bioactive Glass Supraparticles with Tunable Hierarchical Porosity. Langmuir, 34(5), 2063-2072. https://dx.doi.org/10.1021/acs.langmuir.7b03904

MLA:
Egly, Steffen, et al. "Bottom-Up Assembly of Silica and Bioactive Glass Supraparticles with Tunable Hierarchical Porosity." Langmuir 34.5 (2018): 2063-2072.

BibTeX: 

Last updated on 2019-23-08 at 09:17