Prof. Dr. Wolfgang Kreis


Lehrstuhl für Pharmazeutische Biologie


21- Hydroxpregnan-21-O-Malonyltransferasen: Heterologe Expression in Escherichia coli und Saccharomyces cerevisiae, Charakterisierung und Bedeutung für die Cardenolid-Biosynthese
Prof. Dr. Wolfgang Kreis
(01.06.2019 - 31.05.2021)

(The genus Digitalis: Molecular taxonomy, preservation, active constituents and therapeutic applications):
DIGITALIS: The genus Digitalis: Molecular taxonomy, preservation, active constituents and therapeutic applications
Prof. Dr. Wolfgang Kreis
(01.05.2012 - 30.04.2016)

Verbesserung des Meerrettichanbaus
Prof. Dr. Wolfgang Kreis
(01.01.2009 - 31.12.2017)

Publikationen (Download BibTeX)

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Rieck, C., Geiger, D., Munkert, J., Messerschmidt, K., Petersen, J., Strasser, J.,... Kreis, W. (2019). Biosynthetic approach to combine the first steps of cardenolide formation in Saccharomyces cerevisiae. MicrobiologyOpen.
Kreis, W., & Munkert, J. (2019). Exploiting enzyme promiscuity to shape plant specialized metabolism. Journal of Experimental Botany, 70(5), 1435-1445.
Boff, L., Munkert, J., Ottoni, F.M., Schneider, N.F.Z., Ramos, G.S., Kreis, W.,... Simões, C.M.O. (2019). Potential anti-herpes and cytotoxic action of novel semisynthetic digitoxigenin-derivatives. European Journal of Medicinal Chemistry, 167, 546-561.
Schneider, N.F.Z., Cerella, C., Lee, J.-Y., Mazumder, A., Kim, K.R., de Carvalho, A.,... Diederich, M. (2018). Cardiac Glycoside Glucoevatromonoside Induces Cancer Type-specific Cell Death. Frontiers in Pharmacology, 9.
Silva, I.T., Munkert, J., Nolte, E., Schneider, N.F.Z., Rocha, S.C., Ramos, A.C.P.,... Simões, C.M.O. (2018). Cytotoxicity of AMANTADIG - a semisynthetic digitoxigenin derivative - alone and in combination with docetaxel in human hormone-refractory prostate cancer cells and its effect on Na+/K+ -ATPase inhibition. Biomedicine & Pharmacotherapy, 107, 464-474.
Meitinger, N., & Kreis, W. (2018). Development and validation of a quick assay for the total glucosinolate content in horseradish (Armoracia rusticana) using glucose strips and a blood glucose meter. Journal of Applied Botany and Food Quality-Angewandte Botanik, 91, 232-236.
Schmidt, K., Petersen, J., Munkert, J., Egerer-Sieber, C., Hornig, M., Muller, Y., & Kreis, W. (2018). PRISEs (progesterone 5β-reductase and/or iridoid synthase-like 1,4-enone reductases): Catalytic and substrate promiscuity allows for realization of multiple pathways in plant metabolism. Phytochemistry, 156, 9-19.
Yücesan, B., Eker, İ., Lazzarini, L.E.S., Aslam, N., Mohammed, A., Pinto, J.E.B.P.,... Gürel, E. (2018). Shoot-tip Cultivation and Cardenolide Content Analysis of Natural Populations of Digitalis lanata Ehrh. subsp. lanata (wooly foxglove) in Thrace Region. International Journal of Agriculture and Wildlife Science, 4(1), 55-62.
Nolte, E., Wach, S., Silva, I.T., Lukat, S., Ekici, A.B., Munkert, J.,... Lai, X. (2017). A new semisynthetic cardenolide analog 3β-[2-(1-amantadine)-1-on-ethylamine]-digitoxigenin (AMANTADIG) affects G2/M cell cycle arrest and miRNA expression profiles and enhances proapoptotic survivin-2B expression in renal cell carcinoma cell lines. Oncotarget.
Kreis, W., Munkert, J., & De Padua, R.M. (2017). Biossíntese de metabólitos primários e secundários. In Letícia Bispo de Lima (Eds.), Farmacognosia do Produto Natural ao Medicamento. (pp. 147 - 166). Porto Alegre, Brazil: Artmed Editora Ltda..

Zuletzt aktualisiert 2016-02-06 um 16:00