Dr. Dorothee Weikert


Lehrstuhl für Pharmazeutische Chemie

Publications (Download BibTeX)

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Stanek, M., Picard, L.P., Schmidt, M., Kaindl, J., Hübner, H., Bouvier, M.,... Gmeiner, P. (2019). Hybridization of β-Adrenergic Agonists and Antagonists Confers G Protein Bias. Journal of Medicinal Chemistry, 62(10), 5111-5131. https://dx.doi.org/10.1021/acs.jmedchem.9b00349
Di Pizio, A., Waterloo, L., Brox, R., Löber, S., Weikert, D., Behrens, M.,... Niv, M.Y. (2019). Rational design of agonists for bitter taste receptor TAS2R14: from modeling to bench and back. Cellular and Molecular Life Sciences. https://dx.doi.org/10.1007/s00018-019-03194-2
Männel, B., Hübner, H., Möller, D., & Gmeiner, P. (2017). beta-Arrestin biased dopamine D2 receptor partial agonists: Synthesis and pharmacological evaluation. Bioorganic & Medicinal Chemistry, 25(20), 5613-5628. https://dx.doi.org/10.1016/j.bmc.2017.08.037
Möller, D., Banerjee, A., Uzuneser, T., Skultety, M., Huth, T., Plouffe, B.,... Gmeiner, P. (2017). Discovery of G Protein-Biased Dopaminergics with a Pyrazolo[1,5-a]pyridine Substructure. Journal of Medicinal Chemistry, 60(7), 2908-2929. https://dx.doi.org/10.1021/acs.jmedchem.6b01857
Männel, B., Dengler, D., Shonberg, J., Hübner, H., Möller, D., & Gmeiner, P. (2017). Hydroxy-Substituted Heteroarylpiperazines: Novel Scaffolds for beta-Arrestin-Biased D2R Agonists. Journal of Medicinal Chemistry, 60(11), 4693-4713. https://dx.doi.org/10.1021/acs.jmedchem.7b00363
Fish, I., Stößel, A., Eitel, K., Valant, C., Albold, S., Hübner, H.,... Gmeiner, P. (2017). Structure-Based Design and Discovery of New M-2 Receptor Agonists. Journal of Medicinal Chemistry, 60(22), 9239-9250. https://dx.doi.org/10.1021/acs.jmedchem.7b01113
Männel, B., Jaiteh, M., Zeifinan, A., Randakova, A., Möller, D., Hübner, H.,... Carlsson, J. (2017). Structure-Guided Screening for Functionally Selective D-2 Dopamine Receptor Ligands from a Virtual Chemical Library. Acs Chemical Biology, 12(10), 2652-2661. https://dx.doi.org/10.1021/acschembio.7b00493
Tabor, A., Möller, D., Hübner, H., Kornhuber, J., & Gmeiner, P. (2017). Visualization of ligand-induced dopamine D2S and D2L receptor internalization by TIRF microscopy. Scientific Reports, 7, 10894. https://dx.doi.org/10.1038/s41598-017-11436-1
Hübner, H., Schellhorn, T., Gienger, M., Schaab, C., Kaindl, J., Leeb, L.,... Gmeiner, P. (2016). Structure-guided development of heterodimer-selective GPCR ligands. Nature Communications, 7, 12298. https://dx.doi.org/10.1038/ncomms12298
Möller, D., Mohamed, I.A.S., Kling, R., Hübner, H., & Gmeiner, P. (2015). 1,4-Disubstituted aromatic piperazines with high 5-HT2A/D2 selectivity: quantitative structure selectivity investigations, docking, synthesis and biological evaluation. Bioorganic & Medicinal Chemistry, 23, 6195-6209. https://dx.doi.org/10.1016/j.bmc.2015.07.050

Last updated on 2018-16-05 at 04:31

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