Dr. rer. nat. Silke Frey

Department of Medicine 3 – Rheumatology and Immunology

The soluble CD83 protein prevents bone destruction by inhibiting the formation of osteoclasts and inducing resolution of inflammation in arthritis (2022) Royzman D, Andreev D, Stich L, Peckert K, Wild A, Zinser E, Mühl-Zürbes P, et al. Journal article Overexpression of transmembrane TNF drives development of ectopic lymphoid structures in the bone marrow and B cell lineage alterations in experimental spondyloarthritis (2021) Kaaij MH, Rip J, Jeucken KC, Kan YY, van Rooijen CC, Saris J, Pots D, et al. Journal article Importance of the PD-1/PD-L1 Axis for Malignant Transformation and Risk Assessment of Oral Leukoplakia (2021) Ries J, Agaimy A, Wehrhan F, Baran C, Bolze S, Danzer E, Frey S, et al. Journal article Zoledronate causes a systemic shift of macrophage polarization towards M1 in vivo (2021) Weber M, Homm A, Müller S, Frey S, Amann KU, Ries J, Geppert CI, et al. Journal article The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts (2021) Friščić J, Böttcher M, Reinwald C, Bruns H, Wirth B, Popp S, Walker KI, et al. Journal article, Original article Myeloperoxidase Modulates Inflammation in Generalized Pustular Psoriasis and Additional Rare Pustular Skin Diseases (2020) Haskamp S, Bruns H, Hahn M, Hoffmann M, Gregor A, Löhr S, Hahn J, et al. Journal article JAK inhibition increases bone mass in steady-state conditions and ameliorates pathological bone loss by stimulating osteoblast function (2020) Adam S, Simon N, Steffen U, Andes FT, Scholtysek C, Müller D, Weidner D, et al. Journal article The human sialic acid-binding immunoglobulin-like lectin Siglec-9 and its murine homolog Siglec-E control osteoclast activity and bone resorption (2020) Andes FT, Adam S, Hahn M, Aust O, Frey S, Grüneboom A, Nitschke L, et al. Journal article Rare Loss-of-Function Mutation in SERPINA3 in Generalized Pustular Psoriasis (2020) Frey S, Sticht H, Wilsmann-Theis D, Gerschütz A, Wolf K, Löhr S, Haskamp S, et al. Journal article Structural insights into heme binding to IL-36α proinflammatory cytokine (2019) Wißbrock A, Goradia NB, Kumar A, Paul George AA, Kühl T, Bellstedt P, Ramachandran R, et al. Journal article