Dr. Stefan Löber

Lehrstuhl für Pharmazeutische Chemie

Inhibiting a promiscuous GPCR: iterative discovery of bitter taste receptor ligands (2023) Fierro F, Peri L, Hübner H, Tabor-Schkade A, Waterloo L, Löber S, Pfeiffer T, et al. Journal article Discovery of 2-Aminopyrimidines as Potent Agonists for the Bitter Taste Receptor TAS2R14 (2023) Waterloo L, Hübner H, Fierro F, Pfeiffer T, Brox R, Löber S, Weikert D, et al. Journal article The Bitter Taste Receptor TAS2R14 as a Drug Target (2022) Waterloo L, Löber S, Gmeiner P Journal article Presynaptic vesicular accumulation is required for antipsychotic efficacy in psychotic-like rats (2021) Uzuneser T, Weiss EM, Dahlmanns J, Kalinichenko L, Amato D, Kornhuber J, Alzheimer C, et al. Journal article, Original article Structure-based development of caged dopamine D2/D3 receptor antagonists (2020) Gienger M, Hübner H, Löber S, König B, Gmeiner P Journal article Rational design of agonists for bitter taste receptor TAS2R14: from modeling to bench and back (2020) Di Pizio A, Waterloo L, Brox R, Löber S, Weikert D, Behrens M, Gmeiner P, Niv MY Journal article Derivatization of common antidepressant drugs increases inhibition of acid sphingomyelinase and reduces induction of phospholipidosis (2018) Rhein C, Löber S, Gmeiner P, Gulbins E, Tripal P, Kornhuber J Journal article, Original article Structure-based discovery of opioid analgesics with reduced side effects (2016) Manglik A, Lin H, Aryal DK, Mccorvy JD, Dengler D, Corder G, Levit A, et al. Journal article, Original article Spontaneous butenolide ring formation of pregnane-21-O-malonyl hemiesters under mild reaction conditions is facilitated by the 14β-hydroxy group present in all natural cardenolides (2016) Maia de Pádua R, Meitinger N, Hennemann M, Schebitz P, Waibel R, Löber S, Gmeiner P, et al. Journal article, Original article GPCR crystal structures: Medicinal chemistry in the pocket (2015) Shonberg J, Kling R, Gmeiner P, Löber S Journal article, Review article