PD Dr. Wei Xiang


Lehrstuhl für Biochemie und Molekulare Medizin
Medizinische Fakultät

Publications (Download BibTeX)

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Hoffmann, A.-C., Minakaki, G., Menges, S., Salvi, R., Savitskiy, S., Kazman, A.,... Xiang, W. (2019). Extracellular aggregated alpha synuclein primarily triggers lysosomal dysfunction in neural cells prevented by trehalose. Scientific Reports, 9(1). https://dx.doi.org/10.1038/s41598-018-35811-8
Grötsch, B., Lux, A., Rombouts, Y., Hoffmann, A., Andreev, D., Nimmerjahn, F.,... Bozec, A. (2019). Fra1 Controls Rheumatoid Factor Autoantibody Production by Bone Marrow Plasma Cells and the Development of Autoimmune Bone Loss. Journal of Bone and Mineral Research. https://dx.doi.org/10.1002/jbmr.3705
Minakaki, G., Canneva, F., Chevessier, F., Bode, F., Menges, S., Timotius, I.,... Klucken, J. (2019). Treadmill exercise intervention improves gait and postural control in alpha-synuclein mouse models without inducing cerebral autophagy. Behavioural Brain Research, 363, 199-215. https://dx.doi.org/10.1016/j.bbr.2018.11.035
Sommer, A., Maxreiter, F., Krach, F., Fadler, T., Grosch, J., Maroni, M.,... Winner, B. (2018). Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease. Cell Stem Cell, 23(1), 123-+. https://dx.doi.org/10.1016/j.stem.2018.06.015
Prots, I., Grosch, J., Brazdis, R.-M., Simmnacher, K., Veber, V., Havlicek, S.,... Winner, B. (2018). α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies. Proceedings of the National Academy of Sciences of the United States of America, 115(30), 7813-7818. https://dx.doi.org/10.1073/pnas.1713129115
Minakaki, G., Menges, S., Kittel, A., Emmanouilidou, E., Schäffner, I., Barkovits, K.,... Klucken, J. (2017). Autophagy inhibition promotes SNCA/alpha-synuclein release and transfer via extracellular vesicles with a hybrid autophagosome-exosome-like phenotype. Autophagy, 1-61. https://dx.doi.org/10.1080/15548627.2017.1395992
Regensburger, M., Schreglmann, S.R., Stoll, S., Rockenstein, E., Loskarn, S., Xiang, W.,... Winner, B. (2017). Oligomer-prone E57K-mutant alpha-synuclein exacerbates integration deficit of adult hippocampal newborn neurons in transgenic mice. Brain Structure & Function. https://dx.doi.org/10.1007/s00429-017-1561-5
Hoffmann, A., Ettle, B., Bruno, A., Kulinich, A., Hoffmann, A.-C., von Wittgenstein, J.,... Schlachetzki, J. (2016). Alpha-synuclein activates BV2 microglia dependent on its aggregation state. Biochemical and Biophysical Research Communications, 479(4), 881-886. https://dx.doi.org/10.1016/j.bbrc.2016.09.109
Lee, J.-H., Schierer, S., Blume, K., Dindorf, J., Wittki, S., Xiang, W.,... Baur, A. (2016). HIV-Nef and ADAM17-Containing Plasma Extracellular Vesicles Induce and Correlate with Immune Pathogenesis in Chronic HIV Infection. EBioMedicine, 6, 103-13. https://dx.doi.org/10.1016/j.ebiom.2016.03.004
Sommer, A., Fadler, T., Dorfmeister, E., Hoffmann, A.-C., Xiang, W., Winner, B., & Prots, I. (2016). Infiltrating T lymphocytes reduce myeloid phagocytosis activity in synucleinopathy model. Journal of Neuroinflammation, 13(1), 174. https://dx.doi.org/10.1186/s12974-016-0632-5

Last updated on 2016-15-05 at 04:55