Tony Fröhlich



Organisationseinheit


Lehrstuhl für Organische Chemie I
Professur für Organische Chemie


Publikationen (Download BibTeX)


Hahn, F., Fröhlich, T., Frank, T., Bertzbach, L.D., Kohrt, S., Kaufer, B.B.,... Marschall, M. (2018). Artesunate-derived monomeric, dimeric and trimeric experimental drugs - Their unique mechanistic basis and pronounced antiherpesviral activity. Antiviral Research, 152, 104-110. https://dx.doi.org/10.1016/j.antiviral.2018.02.013
Fröhlich, T., Hahn, F., Belmudes, L., Leidenberger, M., Friedrich, O., Kappes, B.,... Tsogoeva, S. (2018). Synthesis of Artemisinin-Derived Dimers, Trimers and Dendrimers: Investigation of Their Antimalarial and Antiviral Activities Including Putative Mechanisms of Action. Chemistry - A European Journal, 24(32), 8103-8113. https://dx.doi.org/10.1002/chem.201800729
Fröhlich, T., Kiss, A., Wolfling, J., Mernyak, E., Kulmany, A.E., Minorics, R.,... Tsogoeva, S. (2018). Synthesis of Artemisinin-Estrogen Hybrids Highly Active against HCMV, P-falciparum, and Cervical and Breast Cancer. Acs Medicinal Chemistry Letters, 9(11), 1128-1133. https://dx.doi.org/10.1021/acsmedchemlett.8b00381
Fröhlich, T., Reiter, P.C., Saeed, M.E.M., Hutterer, C., Hahn, F., Leidenberger, M.,... Tsogoeva, S. (2018). Synthesis of Thymoquinone-Artemisinin Hybrids: New Potent Antileukemia, Antiviral, and Antimalarial Agents. Acs Medicinal Chemistry Letters, 9(6), 534-539. https://dx.doi.org/10.1021/acsmedchemlett.7b00412
Held, F., Guryev, A., Fröhlich, T., Hampel, F., Kahnt, A., Hutterer, C.,... Tsogoeva, S. (2017). Facile access to potent antiviral quinazoline heterocycles with fluorescence properties via merging metal-free domino reactions. Nature Communications, 8. https://dx.doi.org/10.1038/ncomms15071
Fröhlich, T., Reiter, C., Ibrahim, M.M., Beutel, J., Hutterer, C., Zeitträger, I.,... Tsogoeva, S. (2017). Synthesis of Novel Hybrids of Quinazoline and Artemisinin with High Activities against Plasmodium falciparum, Human Cytomegalovirus, and Leukemia Cells. ACS Omega, 2(6), 2422-2431. https://dx.doi.org/10.1021/acsomega.7b00310
Fröhlich, T., Ndreshkjana, B., Muenzner, J.K., Reiter, P.C., Hofmeister, E., Mederer, S.,... Tsogoeva, S. (2017). Synthesis of Novel Hybrids of Thymoquinone and Artemisinin with High Activity and Selectivity Against Colon Cancer. Chemmedchem, 12(3), 226-234. https://dx.doi.org/10.1002/cmdc.201600594
Reiter, P.C., Fröhlich, T., Gruber, L., Hutterer, C., Marschall, M., Voigtländer, C.,... Tsogoeva, S. (2015). Highly potent artemisinin-derived dimers and trimers: Synthesis and evaluation of their antimalarial, antileukemia and antiviral activities. Bioorganic & medicinal chemistry. https://dx.doi.org/10.1016/j.bmc.2015.07.048
Reiter, P.C., Fröhlich, T., Zeino, M., Marschall, M., Bahsi, H., Leidenberger, M.,... Tsogoeva, S. (2015). New efficient artemisinin derived agents against human leukemia cells, human cytomegalovirus and Plasmodium falciparum: 2nd generation 1,2,4-trioxane-ferrocene hybrids. European journal of medicinal chemistry, 97, 164-72. https://dx.doi.org/10.1016/j.ejmech.2015.04.053
Hutterer, C., Niemann, I., Milbradt, J., Fröhlich, T., Reiter, P.C., Kadioglu, O.,... Marschall, M. (2015). The broad-spectrum antiinfective drug artesunate interferes with the canonical nuclear factor kappa B (NF-κB) pathway by targeting RelA/p65. Antiviral Research, 124, 101-109. https://dx.doi.org/10.1016/j.antiviral.2015.10.003

Zuletzt aktualisiert 2019-05-06 um 23:51