Professur für Genetik

Address:
Staudtstraße 5
91058 Erlangen


Publications (Download BibTeX)

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Setz, C.S., Khadour, A., Renna, V., Iype, J., Gentner, E., He, X.,... Jumaa, H. (2019). Pten controls B-cell responsiveness and germinal center reaction by regulating the expression of IgD BCR. EMBO Journal. https://dx.doi.org/10.15252/embj.2018100249
Wagner, F., Brandl, C., Emmerich, C., Mackensen, A., Nitschke, L., & Müller, F. (2018). Myc-Driven, Primary Mouse Lymphoma Expressing Human CD22 Are Highly Infiltrated By Syngeneic Immune Cells and Provide a Unique Model to Test CD22-Targeted Therapies. In BLOOD. San Diego, CA, US: WASHINGTON: AMER SOC HEMATOLOGY.
Silva, I.T., Munkert, J., Nolte, E., Schneider, N.F.Z., Rocha, S.C., Ramos, A.C.P.,... Simões, C.M.O. (2018). Cytotoxicity of AMANTADIG - a semisynthetic digitoxigenin derivative - alone and in combination with docetaxel in human hormone-refractory prostate cancer cells and its effect on Na+/K+ -ATPase inhibition. Biomedicine & Pharmacotherapy, 107, 464-474. https://dx.doi.org/10.1016/j.biopha.2018.08.028
Wild, A., Krzyzak, L., Mattner, J., Winkler, T., Nitschke, L., & Steinkasserer, A. (2018). The CD83 molecule expressed by dendritic cells is a checkpoint to regulate resolution of inflammation as well as homeostasis within periphery and CNS. (pp. 59-60).
Döbbeler, M., Koenig, C., Krzyzak, L., Seitz, C., Wild, A., Ulas, T.,... Lechmann, M. (2018). CD83 expression is essential for Treg cell differentiation and stability. JCI Insight, 3(11). https://dx.doi.org/10.1172/jci.insight.99712
Willebrand, R., Dietschmann, A., Nitschke, L., Krappmann, S., & Vöhringer, D. (2018). Murine eosinophil development and allergic lung eosinophilia are largely dependent on the signaling adaptor GRB2. European Journal of Immunology, 48(11), 1786-1795. https://dx.doi.org/10.1002/eji.201847555
Munkert, J., Santiago Franco, M., Nolte, E., Silva, I.T., Oliveira Castilho, R., Ottoni, F.M.,... De Padua, R.M. (2017). Production of the Cytotoxic Cardenolide Glucoevatromonoside by Semisynthesis and Biotransformation of Evatromonoside by a Digitalis lanata Cell Culture. Planta medica. https://dx.doi.org/10.1055/s-0043-109557
Prescher, H., Schweizer, A., Kuhfeldt, E., Nitschke, L., & Brossmer, R. (2017). New Human CD22/Siglec-2 Ligands with a Triazole Glycoside. Chembiochem : a European journal of chemical biology. https://dx.doi.org/10.1002/cbic.201600707
Prescher, H., Frank, M., Guetgemann, S., Kuhfeldt, E., Schweizer, A., Nitschke, L.,... Brossmer, R. (2017). Design, Synthesis, and Biological Evaluation of Small, High-Affinity Siglec-7 Ligands: Toward Novel Inhibitors of Cancer Immune Evasion. Journal of Medicinal Chemistry, 60(3), 941-956. https://dx.doi.org/10.1021/acs.jmedchem.6b01111
Nolte, E., Wach, S., Silva, I.T., Lukat, S., Ekici, A.B., Munkert, J.,... Lai, X. (2017). A new semisynthetic cardenolide analog 3β-[2-(1-amantadine)-1-on-ethylamine]-digitoxigenin (AMANTADIG) affects G2/M cell cycle arrest and miRNA expression profiles and enhances proapoptotic survivin-2B expression in renal cell carcinoma cell lines. Oncotarget. https://dx.doi.org/10.18632/oncotarget.14644
Lehmann, C., Baranska, A., Heidkamp, G., Kiessling, M., Soulat, D., Krug, A.,... Dudziak, D. (2016). Antigen targeting of Fc-receptors induces strong T cell responses in vivo independent of ITAM signalling. Journal of Investigative Dermatology, 136(9), S223-S223. https://dx.doi.org/10.1016/j.jid.2016.06.384
Özgör, L., Brandl, C., Shock, A., & Nitschke, L. (2016). Epratuzumab modulates B-cell signaling without affecting B-cell numbers or B-cell functions in a mouse model with humanized CD22. European Journal of Immunology, 46(9), 2260-2272. https://dx.doi.org/10.1002/eji.201646383
Schmitt, H., Sell, S., Koch, J., Seefried, M., Sonnewald, S., Daniel, C.,... Nitschke, L. (2016). Siglec-H protects from virus-triggered severe systemic autoimmunity. Journal of Experimental Medicine, 213(8), 1627-1644. https://dx.doi.org/10.1084/jem.20160189
Krzyzak, L., Seitz, C., Urbat, A., Hutzler, S., Ostalecki, C., Glaesner, J.,... Nitschke, L. (2016). CD83 Modulates B Cell Activation and Germinal Center Responses. Journal of Immunology, 196(9), 3581-3594. https://dx.doi.org/10.4049/jimmunol.1502163
Radtke, D., Lacher, S.M., Szumilas, N., Sandrock, L., Ackermann, J., Nitschke, L., & Zinser, E. (2016). Grb2 Is Important for T Cell Development, Th Cell Differentiation, and Induction of Experimental Autoimmune Encephalomyelitis. Journal of Immunology, 196(7), 2995-3005. https://dx.doi.org/10.4049/jimmunol.1501764
Gruber, S., Hendrikx, T., Tsiantoulas, D., Ozsvar-Kozma, M., Goederle, L., Mallat, Z.,... Binder, C.J. (2016). Sialic Acid-Binding Immunoglobulin-like Lectin G Promotes Atherosclerosis and Liver Inflammation by Suppressing the Protective Functions of B-1 Cells. Cell Reports, 14(10), 2348-2361. https://dx.doi.org/10.1016/j.celrep.2016.02.027
Gasparrini, F., Feest, C., Bruckbauer, A., Mattila, P.K., Müller, J., Nitschke, L.,... Batista, F.D. (2016). Nanoscale organization and dynamics of the siglec CD22 cooperate with the cytoskeleton in restraining BCR signalling. Embo Journal, 35(3), 258-280. https://dx.doi.org/10.15252/embj.201593027
Müller, J., Lunz, B., Schwab, I., Acs, A., Nimmerjahn, F., Daniel, C., & Nitschke, L. (2015). Siglec-G Deficiency Leads to Autoimmunity in Aging C57BL/6 Mice. Journal of immunology (Baltimore, Md. : 1950), 195(1), 51-60. https://dx.doi.org/10.4049/jimmunol.1403139
Ludwig, J., Federico, G., Prokosch, S., Kueblbeck, G., Schmitt, S., Klevenz, A.,... Arnold, B. (2015). Dickkopf-3 Acts as a Modulator of B Cell Fate and Function. Journal of Immunology, 194(6), 2624-2634. https://dx.doi.org/10.4049/jimmunol.1402160
Niedzielska, M., Mohamed Raffi, F.A., Tel, J., Muench, S., Jozefowski, K., Alati, N.,... Lang, R. (2015). Selective Expression of the MAPK Phosphatase Dusp9/MKP-4 in Mouse Plasmacytoid Dendritic Cells and Regulation of IFN-? Production. Journal of Immunology, 195(4), 1753-62. https://dx.doi.org/10.4049/jimmunol.1400658

Last updated on 2019-24-04 at 10:28