Lehrstuhl für Klinische Pharmakologie und Klinische Toxikologie

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Fahrstraße 17
91054 Erlangen



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Professur für Klinische Pharmakologie


Publications (Download BibTeX)

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Selch, S., Chafai, A., Sticht, H., Birkenfeld, A.L., Fromm, M., & König, J. (2018). Analysis of naturally occurring mutations in the human uptake transporter NaCT important for bone and brain development and energy metabolism. Scientific Reports, 8(1). https://dx.doi.org/10.1038/s41598-018-29547-8
Pfistermeister, B., Tuemena, T., Gassmann, K.-G., Maas, R., & Fromm, M. (2017). Anticholinergic burden and cognitive function in a large German cohort of hospitalized geriatric patients. PLoS ONE, 12(2). https://dx.doi.org/10.1371/journal.pone.0171353
Kachler, K., Bailer, M., Heim, L., Schumacher, F., Reichel, M., Holzinger, C.D.,... Finotto, S. (2017). Enhanced Acid Sphingomyelinase Activity Drives Immune Evasion and Tumor Growth in Non-Small Cell Lung Carcinoma. Cancer Research, 77(21), 5963-5976. https://dx.doi.org/10.1158/0008-5472.CAN-16-3313
Taghikhani, E.P., Fromm, M., & König, J. (2017). Assays for Analyzing the Role of Transport Proteins in the Uptake and the Vectorial Transport of Substances Affecting Cell Viability. Methods in molecular biology (Clifton, N.J.), 1601, 123-135. https://dx.doi.org/10.1007/978-1-4939-6960-9_11
von Loeffelholz, C., Lieske, S., Neuschäfer-Rube, F., Willmes, D.M., Raschzok, N., Sauer, I.M.,... Birkenfeld, A.L. (2017). The human longevity gene homolog INDY and interleukin-6 interact in hepatic lipid metabolism. Hepatology. https://dx.doi.org/10.1002/hep.29089
Plank-Kiegele, B., Bürkle, T., Müller, F., Patapovas, A., Sonst, A., Pfistermeister, B.,... Maas, R. (2017). Data requirements for the correct identification of medication errors and adverse drug events in patients presenting at an emergency department. Methods of Information in Medicine, 56(4), 276-282. https://dx.doi.org/10.3414/ME16-01-0126
Reznicek, J., Ceckova, M., Cerveny, L., Müller, F., & Staud, F. (2017). Emtricitabine is a substrate of MATE1 but not of OCT1, OCT2, P-gp, BCRP or MRP2 transporters. Xenobiotica, 47(1), 77-85. https://dx.doi.org/10.3109/00498254.2016.1158886
Chafai, A., Fromm, M., König, J., & Maas, R. (2017). The prognostic biomarker L-homoarginine is a substrate of the cationic amino acid transporters CAT1, CAT2A and CAT2B. Scientific Reports, 7(1). https://dx.doi.org/10.1038/s41598-017-04965-2
Mueller, F., Weitz, D., Derdau, V., Sandvoss, M., Mertsch, K., König, J., & Fromm, M. (2017). Contribution of MATE1 to Renal Secretion of the NMDA Receptor Antagonist Memantine. Molecular Pharmaceutics, 14(9), 2991-2998. https://dx.doi.org/10.1021/acs.molpharmaceut.7b00179
Schächtele, S., Tuemena, T., Gassmann, K.-G., Fromm, M., & Maas, R. (2016). Co-Prescription of QT-Interval Prolonging Drugs: An Analysis in a Large Cohort of Geriatric Patients. PLoS ONE, 11(5), e0155649. https://dx.doi.org/10.1371/journal.pone.0155649
Misaka, S., Knop, J., Singer, K., Hoier, E., Keiser, M., Müller, F.,... Fromm, M. (2016). The Nonmetabolized β-Blocker Nadolol Is a Substrate of OCT1, OCT2, MATE1, MATE2-K, and P-Glycoprotein, but Not of OATP1B1 and OATP1B3. Molecular Pharmaceutics, 13(2), 512-9. https://dx.doi.org/10.1021/acs.molpharmaceut.5b00733
Ceckova, M., Reznicek, J., Ptackova, Z., Cerveny, L., Müller, F., Kacerovsky, M.,... Staud, F. (2016). Role of ABC and Solute Carrier Transporters in the Placental Transport of Lamivudine. Antimicrobial Agents and Chemotherapy, 60(9), 5563-72. https://dx.doi.org/10.1128/AAC.00648-16
Burdin, D.V., Kolobov, A.A., Brocker, C., Soshnev, A.A., Samusik, N., Demyanov, A.V.,... Rodionov, R.N. (2016). Diabetes-linked transcription factor HNF4? regulates metabolism of endogenous methylarginines and ?-aminoisobutyric acid by controlling expression of alanine-glyoxylate aminotransferase 2. Scientific Reports, 6, 35503. https://dx.doi.org/10.1038/srep35503
Pfistermeister, B., Sedlmayr, B., Patapovas, A., Suttner, G., Tektas, O., Tarkhov, A.,... Maas, R. (2016). Development of a Standardized Rating Tool for Drug Alerts to Reduce Information Overload. Methods of Information in Medicine, 55(6), 507-515. https://dx.doi.org/10.3414/ME16-01-0003
Stratz, C., Boemicke, T., Younas, I., Kittel, A., Amann, M., Valina, C.M.,... Hochholzer, W. (2016). Comparison of Immature Platelet Count to Established Predictors of Platelet Reactivity During Thienopyridine Therapy. Journal of the American College of Cardiology, 68(3), 286-93. https://dx.doi.org/10.1016/j.jacc.2016.04.056
Gruetz, M., Sticht, H., Gläser, H., Fromm, M., & König, J. (2016). Analysis of amino acid residues in the predicted transmembrane pore influencing transport kinetics of the hepatic drug transporter organic anion transporting polypeptide 1B1 (OATP1B1). BBA - Biochimica et Biophysica Acta, 1858(11), 2894-2902. https://dx.doi.org/10.1016/j.bbamem.2016.08.018
Knop, J., Misaka, S., Singer, K., Hoier, E., Müller, F., Gläser, H.,... Fromm, M. (2015). Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein. PLoS ONE, 10(10), e0139370. https://dx.doi.org/10.1371/journal.pone.0139370
Mueller, F., Pontones, C., Renner, B., Mieth, M., Hoier, E., Auge, D.,... Fromm, M. (2015). N(1)-methylnicotinamide as an endogenous probe for drug interactions by renal cation transporters: studies on the metformin-trimethoprim interaction. European Journal of Clinical Pharmacology, 71(1), 85-94. https://dx.doi.org/10.1007/s00228-014-1770-2
Bexten, M., Oswald, S., Grube, M., Jia, J., Graf, T., Zimmermann, U.,... Keiser, M. (2015). Expression of drug transporters and drug metabolizing enzymes in the bladder urothelium in man and affinity of the bladder spasmolytic trospium chloride to transporters likely involved in its pharmacokinetics. Molecular Pharmaceutics, 12(1), 171-8. https://dx.doi.org/10.1021/mp500532x
Huber, S., Huettner, J.P., Hacker, K., Bernhardt, G., König, J., & Buschauer, A. (2015). Esters of Bendamustine Are by Far More Potent Cytotoxic Agents than the Parent Compound against Human Sarcoma and Carcinoma Cells. PLoS ONE, 10(7), e0133743. https://dx.doi.org/10.1371/journal.pone.0133743

Last updated on 2019-24-04 at 10:28