Lehrstuhl für Klinische Pharmakologie und Klinische Toxikologie

Adresse:
Fahrstraße 17
91054 Erlangen



Untergeordnete Organisationseinheiten

Professur für Klinische Pharmakologie


Publikationen (Download BibTeX)

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Taghikhani, E.P., Maas, R., Fromm, M., & König, J. (2019). The renal transport protein OATP4C1 mediates uptake of the uremic toxin asymmetric dimethylarginine (ADMA) and efflux of cardioprotective L-homoarginine. PLoS ONE, 14(3). https://dx.doi.org/10.1371/journal.pone.0213747
Haberkorn, B., König, J., & Fromm, M. (2019). Expression, localization and functional analysis of cancer type OATP1B3 in different stably transfected cell lines. In NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Stuttgart, GERMANY, DE: NEW YORK: SPRINGER.
Geßner, A., Mieth, M., Maas, R., & Fromm, M. (2019). Simultaneous quantification of 10 endogenous biomarkers of cardiovascular diseases and renal dysfunction in small volume plasma samples by LC-MS/MS. In NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Stuttgart, GERMANY: NEW YORK: SPRINGER.
Deutsch, B., Neumeister, C., Schwantes, U., Fromm, M., & König, J. (2019). Interplay of the Organic Cation Transporters OCT1 and OCT2 with the Apically Localized Export Protein MATE1 for the Polarized Transport of Trospium. Molecular Pharmaceutics, 16(2), 510-517. https://dx.doi.org/10.1021/acs.molpharmaceut.8b00779
Duerr, P., Schlichtig, K., Dörje, F., & Fromm, M. (2019). Medication safety in patients treated with new oral antitumor agents: a prospective, randomized investigation on the impact of intensified clinical pharmaceutical/ clinical pharmacological care on patient safety and well-being (AMBORA-Study - supported by the German Cancer Aid (70112447)). In NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. Stuttgart, GERMANY: NEW YORK: SPRINGER.
Stratz, C., Geßner, A., Fromm, M., Hromek, J., Nuehrenberg, T., Hille, L.,... Trenk, D. (2018). Association of plasma concentration of trimethylamine N-oxide and ADP-induced platelet reactivity after a loading dose of clopidogrel 600 mg in patients undergoing elective PCI. In EUROPEAN HEART JOURNAL (pp. 678-678). Munich, DE: OXFORD: OXFORD UNIV PRESS.
Selch, S., Chafai, A., Sticht, H., Birkenfeld, A.L., Fromm, M., & König, J. (2018). Analysis of naturally occurring mutations in the human uptake transporter NaCT important for bone and brain development and energy metabolism. Scientific Reports, 8(1). https://dx.doi.org/10.1038/s41598-018-29547-8
Mueller, F., Sharma, A., König, J., & Fromm, M. (2018). Biomarkers for In Vivo Assessment of Transporter Function. Pharmacological Reviews, 70(2), 246-277. https://dx.doi.org/10.1124/pr.116.013326
Schlichtig, K., Lechner, P., Grafe, C., Ferstl, B., Fuchs, F., Hein, A.,... Dorje, F. (2018). Medication safety in patients treated with new oral antitumor agents: A prospective, randomized investigation on the impact of intensified clinical pharmaceutical/clinical pharmacological care on patient safety, patient knowledge and patient well-being (AMBORA). Supported by the German Cancer Aid within the Comprehensive Cancer Center Erlangen-EMN. (pp. 198-198).
Abe, O., Ono, T., Sato, H., Mueller, F., Ogata, H., Miura, I.,... Misaka, S. (2018). Role of (-)-epigallocatechin gallate in the pharmacokinetic interaction between nadolol and green tea in healthy volunteers. European Journal of Clinical Pharmacology, 74(6), 775-783. https://dx.doi.org/10.1007/s00228-018-2436-2
Stopfer, P., Giessmann, T., Hohl, K., Hutzel, S., Schmidt, S., Gansser, D.,... Müller, F. (2018). Optimization of a drug transporter probe cocktail: potential screening tool for transporter-mediated drug-drug interactions. British Journal of Clinical Pharmacology, 84(9), 1941-1949. https://dx.doi.org/10.1111/bcp.13609
Ceckova, M., Reznicek, J., Deutsch, B., Fromm, M., & Staud, F. (2018). Efavirenz reduces renal excretion of lamivudine in rats by inhibiting organic cation transporters (OCT, Oct) and multidrug and toxin extrusion proteins (MATE, Mate). PLoS ONE, 13(8). https://dx.doi.org/10.1371/journal.pone.0202706
Mueller, F., Weitz, D., Mertsch, K., König, J., & Fromm, M. (2018). Importance of OCT2 and MATE1 for the Cimetidine-Metformin Interaction: Insights from Investigations of Polarized Transport in Single- And Double-Transfected MDCK Cells with a Focus on Perpetrator Disposition. Molecular Pharmaceutics, 15(8), 3425-3433. https://dx.doi.org/10.1021/acs.molpharmaceut.8b00416
Geßner, A., König, J., & Fromm, M. (2018). Contribution of multidrug and toxin extrusion protein 1 (MATE1) to renal secretion of trimethylamine-N-oxide (TMAO). Scientific Reports, 8(1). https://dx.doi.org/10.1038/s41598-018-25139-8
Grafe, C., Semrau, S., Hein, A., Beckmann, M., Mackensen, A., Dörje, F., & Fromm, M. (2018). Dose adjustment of cisplatin, etoposide, and ifosfamide according to kidney function: a retrospective analysis and implications for medication safety. Naunyn-Schmiedebergs Archives of Pharmacology, 391(2), 219-229. https://dx.doi.org/10.1007/s00210-017-1456-2
Chafai, A., Fromm, M., König, J., & Maas, R. (2017). The prognostic biomarker L-homoarginine is a substrate of the cationic amino acid transporters CAT1, CAT2A and CAT2B. Scientific Reports, 7(1). https://dx.doi.org/10.1038/s41598-017-04965-2
von Loeffelholz, C., Lieske, S., Neuschäfer-Rube, F., Willmes, D.M., Raschzok, N., Sauer, I.M.,... Birkenfeld, A.L. (2017). The human longevity gene homolog INDY and interleukin-6 interact in hepatic lipid metabolism. Hepatology. https://dx.doi.org/10.1002/hep.29089
Reznicek, J., Ceckova, M., Cerveny, L., Müller, F., & Staud, F. (2017). Emtricitabine is a substrate of MATE1 but not of OCT1, OCT2, P-gp, BCRP or MRP2 transporters. Xenobiotica, 47(1), 77-85. https://dx.doi.org/10.3109/00498254.2016.1158886
Kachler, K., Bailer, M., Heim, L., Schumacher, F., Reichel, M., Holzinger, C.D.,... Finotto, S. (2017). Enhanced Acid Sphingomyelinase Activity Drives Immune Evasion and Tumor Growth in Non-Small Cell Lung Carcinoma. Cancer Research, 77(21), 5963-5976. https://dx.doi.org/10.1158/0008-5472.CAN-16-3313
Taghikhani, E.P., Fromm, M., & König, J. (2017). Assays for Analyzing the Role of Transport Proteins in the Uptake and the Vectorial Transport of Substances Affecting Cell Viability. Methods in molecular biology (Clifton, N.J.), 1601, 123-135. https://dx.doi.org/10.1007/978-1-4939-6960-9_11

Zuletzt aktualisiert 2019-24-04 um 10:28