Lehrstuhl für Pharmazeutische Chemie

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Nikolaus-Fiebiger-Str. 10
91058 Erlangen



Untergeordnete Organisationseinheiten

Professur für Pharmazeutische Chemie
Professur für Pharmazeutische Chemie


Publikationen (Download BibTeX)

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Nebel, N., Strauch, B., Maschauer, S., Lasch, R., Rampp, H., Fehler, S.,... Prante, O. (2017). 18F]Fluorophenylazocarboxylates: Design and Synthesis of Potential Radioligands for Dopamine D3 and μ-Opioid Receptor. ACS Omega, 2(12), 8649-8659. https://dx.doi.org/10.1021/acsomega.7b01374
She, X., Pegoli, A., Mayr, J., Hübner, H., Bernhardt, G., Gmeiner, P., & Keller, M. (2017). Heterodimerization of dibenzodiazepinone-type muscarinic acetylcholine receptor ligands leads to increased M2R affinity and selectivity. ACS Omega, 2(10), 6741-6754. https://dx.doi.org/10.1021/acsomega.7b01085
Milanos, L., Saleh, N., Kling, R., Kaindl, J., Tschammer, N., & Clark, T. (2016). Identification of Two Distinct Sites for Antagonist and Biased Agonist Binding to the Human Chemokine Receptor CXCR3. Angewandte Chemie-International Edition, 55(49), 15277-15281. https://dx.doi.org/10.1002/anie.201607831
Tabor, A., Weisenburger, S., Banerjee, A., Purkayastha, N., Kaindl, J., Hübner, H.,... Gmeiner, P. (2016). Visualization and ligand-induced modulation of dopamine receptor dimerization at the single molecule level. Scientific Reports, 6, 33233. https://dx.doi.org/10.1038/srep33233
Manglik, A., Lin, H., Aryal, D.K., Mccorvy, J.D., Dengler, D., Corder, G.,... Shoichet, B.K. (2016). Structure-based discovery of opioid analgesics with reduced side effects. Nature, 537(7619), 185-190. https://dx.doi.org/10.1038/nature19112
Ludwig, J., Ulm, N., Pröschel, M., Sticht, H., Sonnewald, U., & Eichler, J. (2016). CHARACTERIZATION OF THE SPYTAG - SPY-CATCHER INTERACTION. Journal of Peptide Science, 22, S66-S66.
Naporra, F., Gobleder, S., Wittmann, H.-J., Spindler, J., Bodensteiner, M., Bernhardt, G.,... Strasser, A. (2016). Dibenzo[b,f][1,4]oxazepines and dibenzo[b,e]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H1R, H4R, 5-HT2AR and other selected GPCRs. Pharmacological research, 113, 610-625. https://dx.doi.org/10.1016/j.phrs.2016.09.042
Röhrig, W., Waibel, R., Perlwitz, C., Pischetsrieder, M., & Hoch, T. (2016). Identification of the oleic acide ethanolamide (OEA) isomer cis-vaccenic acid ethanolamide (VEA) as a highly abundant 18:1 fatty acid ethanolamide in blood plasma from rats and humans. Analytical and Bioanalytical Chemistry, 408(22), 6141-6151. https://dx.doi.org/10.1007/s00216-016-9720-8
Weichert, D., Stanek, M., Hübner, H., & Gmeiner, P. (2016). Structure-guided development of dual ß2 adrenergic/dopamine D-2 receptor agonists. Bioorganic & Medicinal Chemistry, 24, 2641-2653. https://dx.doi.org/10.1016/j.bmc.2016.04.028
Maia de Pádua, R., Meitinger, N., Hennemann, M., Schebitz, P., Waibel, R., Löber, S.,... Kreis, W. (2016). Spontaneous butenolide ring formation of pregnane-21-O-malonyl hemiesters under mild reaction conditions is facilitated by the 14β-hydroxy group present in all natural cardenolides. Tetrahedron, 72, 4556-4563. https://dx.doi.org/10.1016/j.tet.2016.06.024
Kling, R., Plomer, M., Lang, C., Banerjee, A., Hübner, H., & Gmeiner, P. (2016). Development of Covalent Ligand-Receptor Pairs to Study the Binding Properties of Nonpeptidic Neurotensin Receptor 1 Antagonists. ACS chemical biology, 11(4), 869-875. https://dx.doi.org/10.1021/acschembio.5b00965
Keller, M., Kuhn, K.K., Einsiedel, J., Hübner, H., Biselli, S., Mollereau, C.,... Buschauer, A. (2016). Mimicking of Arginine by Functionalized N(ω)-Carbamoylated Arginine As a New Broadly Applicable Approach to Labeled Bioactive Peptides: High Affinity Angiotensin, Neuropeptide Y, Neuropeptide FF, and Neurotensin Receptor Ligands As Examples. Journal of medicinal chemistry, 59(5), 1925-45. https://dx.doi.org/10.1021/acs.jmedchem.5b01495
Lampros, M., Brox, R., Frank, T., Poklukar, G., Palmisano, R., Waibel, R.,... Tschammer, N. (2016). Discovery and Characterization of Biased Allosteric Agonists of the Chemokine Receptor CXCR3. Journal of medicinal chemistry, 59(5), 2222-43. https://dx.doi.org/10.1021/acs.jmedchem.5b01965
Kling, R., Clark, T., & Gmeiner, P. (2016). Comparative MD Simulations Indicate a Dual Role for Arg132(3.50) in Dopamine-Dependent D2R Activation. PLoS ONE, 11(1). https://dx.doi.org/10.1371/journal.pone.0146612
Frank, T., Reichel, A., Larsen, O., Stilp, A.-C., Rosenkilde, M.M., Stamminger, T.,... Tschammer, N. (2016). Attenuation of chemokine receptor function and surface expression as an immunomodulatory strategy employed by human cytomegalovirus is linked to vGPCR US28. Cell Communication and Signaling, 14(1), 31. https://dx.doi.org/10.1186/s12964-016-0154-x
Admas, T., Bernat, V., Heinrich, M., & Tschammer, N. (2016). Development of Photoactivatable Allosteric Modulators for the Chemokine Receptor CXCR3. ChemMedChem, 11(6), 575-584. https://dx.doi.org/10.1002/cmdc.201500573
Hübner, H., Schellhorn, T., Gienger, M.T., Schaab, C., Kaindl, J., Leeb, L.,... Gmeiner, P. (2016). Structure-guided development of heterodimer-selective GPCR ligands. Nature Communications, 7, 12298. https://dx.doi.org/10.1038/ncomms12298
Maschauer, S., Einsiedel, J., Hübner, H., Gmeiner, P., & Prante, O. (2016). 18F- and 68Ga-Labeled Neurotensin Peptides for PET Imaging of Neurotensin Receptor 1. Journal of Medicinal Chemistry, 59, 6480-6492. https://dx.doi.org/10.1021/acs.jmedchem.6b00675
Nebel, N., Maschauer, S., Hocke, C., Hübner, H., Gmeiner, P., & Prante, O. (2016). Optimization and synthesis of an 18F-labeled dopamine D3 receptor ligand using [18F]fluorophenylazocarboxylic tert-butylester. Journal of Labelled Compounds and Radiopharmaceuticals, 59(2), 48-53. https://dx.doi.org/10.1002/jlcr.3361
Kao, D., Danzer, H., Collin, M., Groß, A., Eichler, J., Stambuk, J.,... Nimmerjahn, F. (2015). A Monosaccharide Residue Is Sufficient to Maintain Mouse and Human IgG Subclass Activity and Directs IgG Effector Functions to Cellular Fc Receptors. Cell Reports, 13(11), 2376-85. https://dx.doi.org/10.1016/j.celrep.2015.11.027

Zuletzt aktualisiert 2019-24-04 um 10:21