Lehrstuhl für Pharmazeutische Chemie

Address:
Nikolaus-Fiebiger-Str. 10
91058 Erlangen



Subordinate Organisational Units

Professur für Pharmazeutische Chemie
Professur für Pharmazeutische Chemie


Publications (Download BibTeX)

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Stanek, M., Picard, L.P., Schmidt, M., Kaindl, J., Hübner, H., Bouvier, M.,... Gmeiner, P. (2019). Hybridization of β-Adrenergic Agonists and Antagonists Confers G Protein Bias. Journal of Medicinal Chemistry, 62(10), 5111-5131. https://dx.doi.org/10.1021/acs.jmedchem.9b00349
Sommer, T., Dlugash, G., Hübner, H., Gmeiner, P., & Pischetsrieder, M. (2019). Monitoring of the dopamine D2 receptor agonists hordenine and N-methyltyramine during the brewing process and in commercial beer samples. Food Chemistry, 276, 745-753. https://dx.doi.org/10.1016/j.foodchem.2018.10.067
Halbig, C.E., Lasch, R., Krüll, J., Pirzer, A., Wang, Z., Kirchhof, J.N.,... Eigler, S. (2019). Selective Functionalization of Graphene at Defect-Activated Sites by Arylazocarboxylic tert-Butyl Esters. Angewandte Chemie International Edition, 58(11), 3599-3603. https://dx.doi.org/10.1002/anie.201811192
Pirzer, A., Alvarez, E.-M., Friedrich, H., & Heinrich, M. (2019). Radical Carbofluorination of Alkenes with Arylhydrazines and Selectfluor: Additives, Mechanistic Pathways, and Polar Effects. Chemistry - A European Journal, 25(11), 2786-2792. https://dx.doi.org/10.1002/chem.201805256
Trushkov, I.V., Uchuskin, M.G., Abaev, V.T., & Serdyuk, O. (2019). Indolylvinyl Ketones: Building Blocks for the Synthesis of Natural Products and Bioactive Compounds. Synthesis-Stuttgart, 51(4), 787-815. https://dx.doi.org/10.1055/s-0037-1611702
Sawengngen, N., Chalikidi, P.N., Araby, S., Hampel, F., Gmeiner, P., & Serdyuk, O. (2019). Synthesis of pyrazolylvinyl ketones from furan derivatives. Organic & Biomolecular Chemistry, 17(19), 4850-4855. https://dx.doi.org/10.1039/c9ob00701f
Fish, I., Stößel, A., Eitel, K., Valant, C., Albold, S., Hübner, H.,... Gmeiner, P. (2017). Structure-Based Design and Discovery of New M-2 Receptor Agonists. Journal of Medicinal Chemistry, 60(22), 9239-9250. https://dx.doi.org/10.1021/acs.jmedchem.7b01113
Männel, B., Hübner, H., Möller, D., & Gmeiner, P. (2017). beta-Arrestin biased dopamine D2 receptor partial agonists: Synthesis and pharmacological evaluation. Bioorganic & Medicinal Chemistry, 25(20), 5613-5628. https://dx.doi.org/10.1016/j.bmc.2017.08.037
Männel, B., Jaiteh, M., Zeifinan, A., Randakova, A., Möller, D., Hübner, H.,... Carlsson, J. (2017). Structure-Guided Screening for Functionally Selective D-2 Dopamine Receptor Ligands from a Virtual Chemical Library. Acs Chemical Biology, 12(10), 2652-2661. https://dx.doi.org/10.1021/acschembio.7b00493
Schwalbe, T., Kaindl, J., Hübner, H., & Gmeiner, P. (2017). Potent haloperidol derivatives covalently binding to the dopamine D2 receptor. Bioorganic & Medicinal Chemistry, 25(19), 5084-5094. https://dx.doi.org/10.1016/j.bmc.2017.06.034
Lachmann, D., Studte, C., Männel, B., Hübner, H., Gmeiner, P., & Koenig, B. (2017). Photochromic Dopamine Receptor Ligands Based on Dithienylethenes and Fulgides. Chemistry - A European Journal, 23(54), 13423-13434. https://dx.doi.org/10.1002/chem.201702147
Hofmann, J., Gans, E., Clark, T., & Heinrich, M. (2017). Radical Arylation of Anilines and Pyrroles via Aryldiazotates. Chemistry - A European Journal, 23(40), 9647-9656. https://dx.doi.org/10.1002/chem.201701429
Männel, B., Dengler, D., Shonberg, J., Hübner, H., Möller, D., & Gmeiner, P. (2017). Hydroxy-Substituted Heteroarylpiperazines: Novel Scaffolds for beta-Arrestin-Biased D2R Agonists. Journal of Medicinal Chemistry, 60(11), 4693-4713. https://dx.doi.org/10.1021/acs.jmedchem.7b00363
Pegoli, A., She, X., Wifling, D., Hübner, H., Bernhardt, G., Gmeiner, P., & Keller, M. (2017). Radiolabeled Dibenzodiazepinone-Type Antagonists Give Evidence of Dualsteric Binding at the M-2 Muscarinic Acetylcholine Receptor. Journal of Medicinal Chemistry, 60(8), 3314-3334. https://dx.doi.org/10.1021/acs.jmedchem.6b01892
Möller, D., Banerjee, A., Uzuneser, T., Skultety, M., Huth, T., Plouffe, B.,... Gmeiner, P. (2017). Discovery of G Protein-Biased Dopaminergics with a Pyrazolo[1,5-a]pyridine Substructure. Journal of Medicinal Chemistry, 60(7), 2908-2929. https://dx.doi.org/10.1021/acs.jmedchem.6b01857
Sommer, T., Hübner, H., El Kerdawy, A., Gmeiner, P., Pischetsrieder, M., & Clark, T. (2017). Identification of the Beer Component Hordenine as Food-Derived Dopamine D2 Receptor Agonist by Virtual Screening a 3D Compound Database. Scientific Reports, 7, 44201. https://dx.doi.org/10.1038/srep44201
Simeth, N.A., Bause, M., Dobmeier, M., Kling, R., Lachmann, D., Hübner, H.,... Koenig, B. (2017). NTS2-selective neurotensin mimetics with tetrahydrofuran amino acids. Bioorganic & Medicinal Chemistry, 25(1), 350-359. https://dx.doi.org/10.1016/j.bmc.2016.10.039
Stößel, A., Brox, R., Purkayastha, N., Hübner, H., Hocke, C., Prante, O., & Gmeiner, P. (2017). Development of molecular tools based on the dopamine D3 receptor ligand FAUC 329 showing inhibiting effects on drug and food maintained behavior. Bioorganic & Medicinal Chemistry, 25(13), 3491-3499. https://dx.doi.org/10.1016/j.bmc.2017.04.036
Nebel, N., Strauch, B., Maschauer, S., Lasch, R., Rampp, H., Fehler, S.,... Prante, O. (2017). [18F]Fluorophenylazocarboxylates: Design and Synthesis of Potential Radioligands for Dopamine D3 and μ‑Opioid Receptor. ACS Omega, 2, 8649-8659. https://dx.doi.org/10.1021/acsomega.7b01374
Fröhlich, T., Reiter, C., Ibrahim, M.M., Beutel, J., Hutterer, C., Zeitträger, I.,... Tsogoeva, S. (2017). Synthesis of Novel Hybrids of Quinazoline and Artemisinin with High Activities against Plasmodium falciparum, Human Cytomegalovirus, and Leukemia Cells. ACS Omega, 2(6), 2422-2431. https://dx.doi.org/10.1021/acsomega.7b00310

Last updated on 2019-24-04 at 10:21