Emil-Fischer-Zentrum (Emil Fischer Center)


Beschreibung:Emil-Fischer-Zentrum (Emil Fischer Center)
Adresse:
Schlossplatz 4
91054 Erlangen


Publikationen (Download BibTeX)

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Dietrich, P., Gaza, A., Wormser, L., Fritz, V., Hellerbrand, C., & Boßerhoff, A.K. (2019). Neuroblastoma RAS Viral Oncogene Homolog (NRAS) Is a Novel Prognostic Marker and Contributes to Sorafenib Resistance in Hepatocellular Carcinoma. Neoplasia, 21(3), 257-268. https://dx.doi.org/10.1016/j.neo.2018.11.011
Fiebig, C., Keiner, S., Ebert, B., Schäffner, I., Jagasia, R., Lie, D.C., & Beckervordersandforth, R. (2019). Mitochondrial Dysfunction in Astrocytes Impairs the Generation of Reactive Astrocytes and Enhances Neuronal Cell Death in the Cortex Upon Photothrombotic Lesion. Frontiers in Molecular Neuroscience, 12. https://dx.doi.org/10.3389/fnmol.2019.00040
Mahli, A., Koch, A., Fresse, K., Schiergens, T., Thasler, W.E., Schoenberger, C.,... Hellerbrand, C. (2018). Iso-alpha acids from hops (Humulus lupulus) inhibit hepatic steatosis, inflammation, and fibrosis. Laboratory Investigation, 98(12), 1614-1626. https://dx.doi.org/10.1038/s41374-018-0112-x
Prots, I., Grosch, J., Brazdis, R.-M., Simmnacher, K., Veber, V., Havlicek, S.,... Winner, B. (2018). α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies. Proceedings of the National Academy of Sciences, 115(30), 7813-7818. https://dx.doi.org/10.1073/pnas.1713129115
Turnescu, T., Arter, J., Reiprich, S., Tamm, E.R., Reiprich, S., Waisman, A., & Wegner, M. (2018). Sox8 and Sox10 jointly maintain myelin gene expression in oligodendrocytes. Glia, 66(66), 279-294. https://dx.doi.org/10.1002/glia.23242
Schummer, P., Kuphal, S., Vardimon, L., Boßerhoff, A.K., & Kappelmann, M. (2016). Specific c-Jun target genes in malignant melanoma. Cancer Biology & Therapy, 17(5), 486-97. https://dx.doi.org/10.1080/15384047.2016.1156264
Baroti, T., Schillinger, A., Wegner, M., & Stolt, C. (2016). Sox13 functionally complements the related Sox5 and Sox6 as important developmental modulators in mouse spinal cord oligodendrocytes. Journal of Neurochemistry, 136(2), 316-28. https://dx.doi.org/10.1111/jnc.13414
Baroti, T., Zimmermann, Y., Schillinger, A., Liu, L., Lommes, P., Wegner, M., & Stolt, C. (2016). Transcription factors Sox5 and Sox6 exert direct and indirect influences on oligodendroglial migration in spinal cord and forebrain. Glia, 64(1), 122-38. https://dx.doi.org/10.1002/glia.22919
Voeller, D., Linck, L., Bruckmann, A., Hauptmann, J., Deutzmann, R., Meister, G., & Boßerhoff, A.K. (2016). Argonaute Family Protein Expression in Normal Tissue and Cancer Entities. PLoS ONE, 11(8), e0161165. https://dx.doi.org/10.1371/journal.pone.0161165
Denzer-Lippmann, M., Bachlechner, S., Wielopolski, J., Fischer, M., Büttner, A., Dörfler, A.,... Thürauf, N. (2016). Effect of oral bolus versus sustained release application of nutrient solution on olfaction. (pp. 410-411).
Werdehausen, R., Mittnacht, S., Bee, L.A., Minett, M.S., Armbruster, A., Bauer, I.,... Eulenburg, V. (2015). The lidocaine metabolite N-ethylglycine has antinociceptive effects in experimental inflammatory and neuropathic pain. Pain, 156(9), 1647-59. https://dx.doi.org/10.1097/j.pain.0000000000000206
Linck, L., Binder, J., Haynl, C., & Enz, R. (2015). Endocytosis of GABA(C) receptors depends on subunit composition and is regulated by protein kinase C-? and protein phosphatase 1. Journal of Neurochemistry, 134(2), 233-46. https://dx.doi.org/10.1111/jnc.13126
Weider, M., Wegener, A., Schmitt-Engel, C., Küspert, M., Hillgaertner, S., Boesl, M.R.,... Wegner, M. (2015). Elevated in vivo levels of a single transcription factor directly convert satellite glia into oligodendrocyte-like cells. Plos Genetics, 11(2), e1005008. https://dx.doi.org/10.1371/journal.pgen.1005008
Andreu, Z., Khan, M.A., Gonzalez-Gomez, P., Negueruela, S., Hortigueela, R., Emeterio, J.S.,... Mira, H. (2015). The cyclin-dependent kinase inhibitor p27 kip1 regulates radial stem cell quiescence and neurogenesis in the adult hippocampus. Stem Cells, 33(1), 219-29. https://dx.doi.org/10.1002/stem.1832
Meiselbach, H., Vogel, N., Langlhofer, G., Stangl, S., Schleyer, B., Bahnassawy, L.,... Villmann, C. (2014). Single expressed glycine receptor domains reconstitute functional ion channels without subunit-specific desensitization behavior. Journal of Biological Chemistry, 289(42), 29135-47. https://dx.doi.org/10.1074/jbc.M114.559138
Hoffmann, S.A., Hos, D., Küspert, M., Lang, R.A., Lovell-Badge, R., Wegner, M., & Reiprich, S. (2014). Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes. Development, 141(1), 39-50. https://dx.doi.org/10.1242/dev.098418
Hartmann, C., Mayenzet, F., Larcinese, J.-P., Haefliger, O.P., Büttner, A.K., & Starkenmann, C. (2013). Development of an analytical approach for identification and quantification of 5-alpha-androst-16-en-3-one in human milk. Steroids, 78(2), 156-160. https://dx.doi.org/10.1016/j.steroids.2012.11.005
Xiang, W., Schlachetzki, J., Helling, S., Bussmann, J.C., Berlinghof, M., Schäffer, T.,... Klucken, J. (2013). Oxidative stress-induced posttranslational modifications of alpha-synuclein: specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity. Molecular and Cellular Neuroscience, 54, 71-83. https://dx.doi.org/10.1016/j.mcn.2013.01.004
Xiang, W., Weisbach, V.G., Sticht, H., Seebahn, A., Bussmann, J., Zimmermann, R., & Becker, C.-M. (2013). Oxidative stress-induced posttranslational modifications of human hemoglobin in erythrocytes. Archives of Biochemistry and Biophysics, 529(1), 34-44. https://dx.doi.org/10.1016/j.abb.2012.11.002
Meyer, B., Al-Diab, D., Vollmer, G., & Pischetsrieder, M. (2011). Mapping the glycoxidation product Nepsilon-carboxymethyllysine in the milk proteome. Proteomics, 11, 420-428. https://dx.doi.org/10.1002/pmic.201000233


Zusätzliche Publikationen (Download BibTeX)

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Östreicher, C., Gensberger-Reigl, S., & Pischetsrieder, M. (2019). Targeted mass spectrometry to monitor nuclear accumulation of endogenous Nrf2 and its application to SH-SY5Y cells stimulated with food components. Analytical and Bioanalytical Chemistry, 411(6), 1273-1286. https://dx.doi.org/10.1007/s00216-018-1560-2
Schulz, C., Chiheb, C., & Pischetsrieder, M. (2019). Quantification of co-, n-, and ad-lupulone in hop-based dietary supplements and phytopharmaceuticals and modulation of their contents by the extraction method. Journal of Pharmaceutical and Biomedical Analysis, 168, 124-132. https://dx.doi.org/10.1016/j.jpba.2019.02.022
Liu, Y., & Pischetsrieder, M. (2018). Absolute quantification of two antimicrobial peptides alpha(S2)-casein(182-207) and alpha(S2)-casein(151-181) in bovine milk by UHPLC-ESI-MS/MS in sMRM mode. Food Chemistry, 261, 15-20. https://dx.doi.org/10.1016/j.foodchem.2018.04.004
Mahmoud, M., Tybussek, T., Loos, H., Wagenstaller, M., & Büttner, A.K. (2018). Odorants in Fish Feeds: A Potential Source of Malodors in Aquaculture. Frontiers in Chemistry, 6. https://dx.doi.org/10.3389/fchem.2018.00241
Schreiner, L., Bauer, P., & Büttner, A. (2018). Resolving the smell of wood - identification of odour-active compounds in Scots pine (Pinus sylvestris L.). Scientific Reports, 8. https://dx.doi.org/10.1038/s41598-018-26626-8
Kröner, E.-M., & Büttner, A.K. (2018). Sensory-Analytical Comparison of the Aroma of Different Horseradish Varieties (Armoracia rusticana). Frontiers in Chemistry, 6. https://dx.doi.org/10.3389/fchem.2018.00149
Denk, P., & Büttner, A.K. (2018). Identification and quantification of glue-like off-odors in elastic therapeutic tapes. Analytical and Bioanalytical Chemistry, 410(14), 3395-3404. https://dx.doi.org/10.1007/s00216-018-1046-2
Rich, C.A., Perera, S.N., Andratschke, J., Stolt, C., Buehler, D.P., Southard-Smith, E.M.,... Baker, C.V.H. (2018). Olfactory ensheathing cells abutting the embryonic olfactory bulb express Frzb, whose deletion disrupts olfactory axon targeting. Glia, 66(12), 2617-2631. https://dx.doi.org/10.1002/glia.23515
Weider, M., Starost, L.J., Groll, K., Küspert, M., Sock, E., Wedel, M.,... Wegner, M. (2018). Publisher Correction: Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning. Nature Communications, 9(1). https://dx.doi.org/10.1038/s41467-018-03871-z
Dietrich, P., Kuphal, S., Spruss, T., Hellerbrand, C., & Boßerhoff, A.K. (2018). MicroRNA-622 is a novel mediator of tumorigenicity in melanoma by targeting Kirsten rat sarcoma. Pigment Cell & Melanoma Research. https://dx.doi.org/10.1111/pcmr.12698
Fish, I., Stößel, A., Eitel, K., Valant, C., Albold, S., Hübner, H.,... Gmeiner, P. (2017). Structure-Based Design and Discovery of New M-2 Receptor Agonists. Journal of Medicinal Chemistry, 60(22), 9239-9250. https://dx.doi.org/10.1021/acs.jmedchem.7b01113
Männel, B., Hübner, H., Möller, D., & Gmeiner, P. (2017). beta-Arrestin biased dopamine D2 receptor partial agonists: Synthesis and pharmacological evaluation. Bioorganic & Medicinal Chemistry, 25(20), 5613-5628. https://dx.doi.org/10.1016/j.bmc.2017.08.037
Kröner, E.-M., & Büttner, A.K. (2017). Unravelling important odorants in horseradish (Armoracia rusticana). Food Chemistry, 232, 455-465. https://dx.doi.org/10.1016/j.foodchem.2017.04.042
Männel, B., Jaiteh, M., Zeifinan, A., Randakova, A., Möller, D., Hübner, H.,... Carlsson, J. (2017). Structure-Guided Screening for Functionally Selective D-2 Dopamine Receptor Ligands from a Virtual Chemical Library. Acs Chemical Biology, 12(10), 2652-2661. https://dx.doi.org/10.1021/acschembio.7b00493
Schwalbe, T., Kaindl, J., Hübner, H., & Gmeiner, P. (2017). Potent haloperidol derivatives covalently binding to the dopamine D2 receptor. Bioorganic & Medicinal Chemistry, 25(19), 5084-5094. https://dx.doi.org/10.1016/j.bmc.2017.06.034
Lachmann, D., Studte, C., Männel, B., Hübner, H., Gmeiner, P., & Koenig, B. (2017). Photochromic Dopamine Receptor Ligands Based on Dithienylethenes and Fulgides. Chemistry - A European Journal, 23(54), 13423-13434. https://dx.doi.org/10.1002/chem.201702147
Östreicher, C., Bartenbacher, S., & Pischetsrieder, M. (2017). Targeted proteome analysis with isotope-coded protein labels for monitoring the influence of dietary phytochemicals on the expression of cytoprotective proteins in primary human colon cells. Journal of Proteomics, 166, 27-38. https://dx.doi.org/10.1016/j.jprot.2017.06.023
Männel, B., Dengler, D., Shonberg, J., Hübner, H., Möller, D., & Gmeiner, P. (2017). Hydroxy-Substituted Heteroarylpiperazines: Novel Scaffolds for beta-Arrestin-Biased D2R Agonists. Journal of Medicinal Chemistry, 60(11), 4693-4713. https://dx.doi.org/10.1021/acs.jmedchem.7b00363
Pegoli, A., She, X., Wifling, D., Hübner, H., Bernhardt, G., Gmeiner, P., & Keller, M. (2017). Radiolabeled Dibenzodiazepinone-Type Antagonists Give Evidence of Dualsteric Binding at the M-2 Muscarinic Acetylcholine Receptor. Journal of Medicinal Chemistry, 60(8), 3314-3334. https://dx.doi.org/10.1021/acs.jmedchem.6b01892
Möller, D., Banerjee, A., Uzuneser, T., Skultety, M., Huth, T., Plouffe, B.,... Gmeiner, P. (2017). Discovery of G Protein-Biased Dopaminergics with a Pyrazolo[1,5-a]pyridine Substructure. Journal of Medicinal Chemistry, 60(7), 2908-2929. https://dx.doi.org/10.1021/acs.jmedchem.6b01857

Zuletzt aktualisiert 2017-19-01 um 01:00