Professur für Virologie

Address:
Schlossgarten 4
91054 Erlangen


Publications (Download BibTeX)


Mukherjee, S., Ghosh, K., Hahn, F., Wangen, C., Strojan, H., Müller, R.,... Ray, S. (2019). Chemically sulfated polysaccharides from natural sources: Assessment of extraction-sulfation efficiencies, structural features and antiviral activities. International Journal of Biological Macromolecules, 136, 521-530. https://dx.doi.org/10.1016/j.ijbiomac.2019.05.005
Guryev, A., Hahn, F., Marschall, M., & Tsogoeva, S. (2019). Visible-Light-Driven C-H Oxidation of Cyclic Tertiary Amines: Access to Synthetic Strychnos Alkaloids with Antiviral Activity. Chemistry - A European Journal, 25(16), 4062-4066. https://dx.doi.org/10.1002/chem.201900078
Capci Karagoez, A., Leidenberger, M., Hahn, F., Friedrich, O., Hampel, F., Marschall, M.,... Tsogoeva, S. (2019). Synthesis of new betulinic acid/betulin-derived dimers and hybrids with potent antimalarial and antiviral activities. Bioorganic & Medicinal Chemistry, 27(1), 110-115. https://dx.doi.org/10.1016/j.bmc.2018.11.018
Steingruber, M., Keller, L., Socher, E., Ferre, S., Hesse, A.-M., Coute, Y.,... Marschall, M. (2019). Cyclins B1, T1, and H differ in their molecular mode of interaction with cytomegalovirus protein kinase pUL97. Journal of Biological Chemistry, 294(15), 6188-6203. https://dx.doi.org/10.1074/jbc.RA118.007049
Fröhlich, T., Kiss, A., Wolfling, J., Mernyak, E., Kulmany, A.E., Minorics, R.,... Tsogoeva, S. (2018). Synthesis of Artemisinin-Estrogen Hybrids Highly Active against HCMV, P-falciparum, and Cervical and Breast Cancer. Acs Medicinal Chemistry Letters, 9(11), 1128-1133. https://dx.doi.org/10.1021/acsmedchemlett.8b00381
Fröhlich, T., Hahn, F., Belmudes, L., Leidenberger, M., Friedrich, O., Kappes, B.,... Tsogoeva, S. (2018). Synthesis of Artemisinin-Derived Dimers, Trimers and Dendrimers: Investigation of Their Antimalarial and Antiviral Activities Including Putative Mechanisms of Action. Chemistry - A European Journal, 24(32), 8103-8113. https://dx.doi.org/10.1002/chem.201800729
Fröhlich, T., Reiter, C., Saeed, M.E.M., Hutterer, C., Hahn, F., Leidenberger, M.,... Tsogoeva, S. (2018). Synthesis of Thymoquinone-Artemisinin Hybrids: New Potent Antileukemia, Antiviral, and Antimalarial Agents. Acs Medicinal Chemistry Letters, 9(6), 534-539. https://dx.doi.org/10.1021/acsmedchemlett.7b00412
Schmalen, A., Karius-Fischer, J., Rauch, P., Setz, C., Korn, K., Henklein, P.,... Schubert, U. (2018). The N-Terminus of the HIV-1 p6 Gag Protein Regulates Susceptibility to Degradation by IDE. Viruses-Basel, 10(12). https://dx.doi.org/10.3390/v10120710
Hahn, F., Fröhlich, T., Frank, T., Bertzbach, L.D., Kohrt, S., Kaufer, B.B.,... Marschall, M. (2018). Artesunate-derived monomeric, dimeric and trimeric experimental drugs - Their unique mechanistic basis and pronounced antiherpesviral activity. Antiviral Research, 152, 104-110. https://dx.doi.org/10.1016/j.antiviral.2018.02.013
Capci Karagoez, A., Reiter, C., Seo, E.-J., Gruber, L., Hahn, F., Leidenberger, M.,... Tsogoeva, S. (2018). Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin. Bioorganic & Medicinal Chemistry, 26(12), 3610-3618. https://dx.doi.org/10.1016/j.bmc.2018.05.041
Hahn, F., Hutterer, C., Henry, C., Hamilton, S.T., Strojan, H., Kraut, A.,... Marschall, M. (2018). Novel cytomegalovirus-inhibitory compounds of the class pyrrolopyridines show a complex pattern of target binding that suggests an unusual mechanism of antiviral activity. Antiviral Research, 159, 84-94. https://dx.doi.org/10.1016/j.antiviral.2018.09.012
Hahn, F., Schmalen, A., Setz, C., Friedrich, M., Schlößer, S., Kölle, J.,... Schubert, U. (2017). Proteolysis of mature HIV-1 p6 Gag protein by the insulin-degrading enzyme (IDE) regulates virus replication in an Env-dependent manner. PLoS ONE, 12(4). https://dx.doi.org/10.1371/journal.pone.0174254
Setz, C., Friedrich, M., Rauch, P., Fraedrich, K., Matthaei, A., Traxdorf, M., & Schubert, U. (2017). Inhibitors of Deubiquitinating Enzymes Block HIV-1 Replication and Augment the Presentation of Gag-Derived MHC-I Epitopes. Viruses-Basel, 9(8). https://dx.doi.org/10.3390/v9080222
Friedrich, M., Setz, C., Hahn, F., Matthaei, A., Fraedrich, K., Rauch, P.,... Schubert, U. (2016). Glutamic Acid Residues in HIV-1 p6 Regulate Virus Budding and Membrane Association of Gag. Viruses-Basel, 8(4), 117. https://dx.doi.org/10.3390/v8040117
Greiner, T., Bolduan, S., Hertel, B., Gro, C., Hamacher, K., Schubert, U.,... Thiel, G. (2016). Ion Channel Activity of Vpu Proteins Is Conserved throughout Evolution of HIV-1 and SIV. Viruses-Basel, 8(12). https://dx.doi.org/10.3390/v8120325
Bolduan, S., Reif, T., Schindler, M., & Schubert, U. (2014). HIV-1 Vpu mediated downregulation of CD155 requires alanine residues 10, 14 and 18 of the transmembrane domain. Virology, 464-465, 375-84. https://dx.doi.org/10.1016/j.virol.2014.07.034
Hahn, F., Setz, C., Friedrich, M., Rauch, P., Solbak, S.M., Froystein, N.A.,... Schubert, U. (2014). Mutation of the highly conserved Ser-40 of the HIV-1 p6 gag protein to Phe causes the formation of a hydrophobic patch, enhances membrane association, and polyubiquitination of Gag. Viruses-Basel, 6(10), 3738-65. https://dx.doi.org/10.3390/v6103738

Last updated on 2019-24-04 at 10:30