British Columbia Cancer Agency


Public institution / office

Location:
Vancouver, Canada


Publications in cooperation with FAU scientists


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Buckley, M.A., Woods, N.T., Tyrer, J.P., Mendoza-Fandino, G., Lawrenson, K., Hazelett, D.J.,... Freedman, M.L. (2019). Functional Analysis and Fine Mapping of the 9p22.2 Ovarian Cancer Susceptibility Locus. Cancer Research, 79(3). https://dx.doi.org/10.1158/0008-5472.CAN-17-3864
Yang, Y., Wu, L., Shu, X., Lu, Y., Shu, X.-O., Cai, Q.,... Long, J. (2019). Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk. Cancer Research, 79(3). https://dx.doi.org/10.1158/0008-5472.CAN-18-2726
Xue, Y., Meehan, B., Fu, Z., Wang, X.Q.D., Fiset, P.O., Rieker, R.,... Huang, S. (2019). SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer. Nature Communications, 10. https://dx.doi.org/10.1038/s41467-019-08380-1
Kelemen, L.E., Earp, M., Fridley, B.L., Chenevix-Trench, G., Fasching, P., Beckmann, M.,... Berchuck, A. (2018). rs495139 in the TYMS-ENOSF1 Region and Risk of Ovarian Carcinoma of Mucinous Histology. International Journal of Molecular Sciences, 19(9). https://dx.doi.org/10.3390/ijms19092473
Earp, M., Tyrer, J.P., Winham, S.J., Lin, H.-Y., Chornokur, G., Dennis, J.,... Phelan, C.M. (2018). Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility. PLoS ONE, 13(7). https://dx.doi.org/10.1371/journal.pone.0197561
Glubb, D.M., Johnatty, S.E., Quinn, M.C.J., O'Mara, T.A., Tyrer, J.P., Gao, B.,... Chenevix-Trench, G. (2017). Analyses of germline variants associated with ovarian cancer survival identify functional candidates at the 1q22 and 19p12 outcome loci. Oncotarget, 8(39), 64670-64684. https://dx.doi.org/10.18632/oncotarget.18501
Kar, S.P., Adler, E., Tyrer, J., Hazelett, D., Anton-Culver, H., Bandera, E.V.,... Lawrenson, K. (2017). Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci. British Journal of Cancer, 116(4), 524-535. https://dx.doi.org/10.1038/bjc.2016.426
Dixon, S.C., Nagle, C.M., Thrift, A.P., Pharoah, P.D.P., Pearce, C.L., Zheng, W.,... Webb, P.M. (2016). Adult body mass index and risk of ovarian cancer by subtype: a Mendelian randomization study. International Journal of Epidemiology, 45(3), 884-95. https://dx.doi.org/10.1093/ije/dyw158
Cuellar-Partida, G., Lu, Y., Dixon, S.C., Fasching, P.A., Hein, A., Burghaus, S.,... Macgregor, S. (2016). Assessing the genetic architecture of epithelial ovarian cancer histological subtypes. Human genetics, 135(7), 741-56. https://dx.doi.org/10.1007/s00439-016-1663-9
Hampras, S.S., Sucheston-Campbell, L.E., Cannioto, R., Chang-Claude, J., Modugno, F., Doerk, T.,... Moysich, K.B. (2016). Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer. Oncotarget. https://dx.doi.org/10.18632/oncotarget.10215
Ong, J.-S., Cuellar-Partida, G., Lu, Y., Fasching, P.A., Hein, A., Burghaus, S.,... Macgregor, S. (2016). Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study. International Journal of Epidemiology, 45(5), 1619-1630. https://dx.doi.org/10.1093/ije/dyw207
Shvab, A., Haase, G., Ben-Shmuel, A., Gavert, N., Brabletz, T., Dedhar, S., & Ben-Ze'Ev, A. (2016). Induction of the intestinal stem cell signature gene SMOC-2 is required for L1-mediated colon cancer progression. Oncogene, 35(5), 549-57. https://dx.doi.org/10.1038/onc.2015.127
Permuth, J.B., Reid, B., Earp, M., Chen, Y.A., Monteiro, A.N.A., Chen, Z.,... Sellers, T.A. (2016). Inherited variants affecting RNA editing may contribute to ovarian cancer susceptibility: results from a large-scale collaboration. Oncotarget, 7(45), 72381-72394. https://dx.doi.org/10.18632/oncotarget.10546
Crump, M., Leppa, S., Fayad, L., Lee, J.J., Di Rocco, A., Ogura, M.,... Habermann, T. (2016). Randomized, Double-Blind, Phase III Trial of Enzastaurin Versus Placebo in Patients Achieving Remission After First-Line Therapy for High-Risk Diffuse Large B-Cell Lymphoma. Journal of Clinical Oncology, 34(21), 2484-92. https://dx.doi.org/10.1200/JCO.2015.65.7171
Kovar, H., Amatruda, J., Brunet, E., Burdach, S., Cidre-Aranaz, F., De Alava, E.,... Delattre, O. (2016). The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease. Oncotarget, 7(8), 8613-24. https://dx.doi.org/10.18632/oncotarget.6937
Lawrenson, K., Li, Q., Kar, S., Seo, J.-H., Tyrer, J., Spindler, T.J.,... Defazio, A. (2015). Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer. Nature Communications, 6, 8234. https://dx.doi.org/10.1038/ncomms9234
Chornokur, G., Lin, H.-Y., Tyrer, J.P., Lawrenson, K., Dennis, J., Amankwah, E.K.,... Phelan, C.M. (2015). Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk. PLoS ONE, 10(6), e0128106. https://dx.doi.org/10.1371/journal.pone.0128106
Lawrenson, K., Iversen, E.S., Tyrer, J., Weber, R.P., Concannon, P., Hazelett, D.J.,... Schildkraut, J.M. (2015). Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer. Carcinogenesis, 36(11), 1341-53. https://dx.doi.org/10.1093/carcin/bgv138
Amankwah, E.K., Lin, H.-Y., Tyrer, J.P., Lawrenson, K., Dennis, J., Chornokur, G.,... Phelan, C.M. (2015). Epithelial-Mesenchymal Transition (EMT) Gene Variants and Epithelial Ovarian Cancer (EOC) Risk. Genetic Epidemiology, 39(8), 689-97. https://dx.doi.org/10.1002/gepi.21921
Lee, A.W., Tyrer, J.P., Doherty, J.A., Stram, D.A., Kupryjanczyk, J., Dansonka-Mieszkowska, A.,... Pearce, C.L. (2015). Evaluating the ovarian cancer gonadotropin hypothesis: a candidate gene study. Gynecologic Oncology, 136(3), 542-8. https://dx.doi.org/10.1016/j.ygyno.2014.12.017

Last updated on 2016-17-11 at 16:29