Victor Chang Cardiac Research Institute


Research facility

Location:
Sydney, Australia


Research projects with FAU researchers

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Application of an IsoStretcher biomechatronics platform and engineering of a novel parallelized MultiStretcher technology for studies of cardiac mechano-signaling in HL-1 atrial cardiomyocytes
Prof. Dr. Dr. Oliver Friedrich; Prof. Boris Martinac
(01/07/2019 - 30/06/2022)
Piezo'ing the heart - novel molecular cardiac mechano-biosensors
Prof. Dr. Dr. Oliver Friedrich
(01/01/2018 - 31/12/2019)
Mechanotransduktion in Endothel- und Herzmuskelzellen bei multidirektionalem Dehnungsstress unter Verwendung einer neuen isotropen `Cell-Stretch`Technologie
Prof. Dr. Dr. Oliver Friedrich
(01/10/2017 - 30/09/2020)
PPP Australia - Mechanotransduction pathways in cardiac hypertrophy
Prof. Dr. Dr. Oliver Friedrich
(01/01/2014 - 31/12/2015)
PPP Australia - Mechanotransduction and Ca2+-regulation in contracting cardiomyocytes
Prof. Dr. Dr. Oliver Friedrich
(01/01/2012 - 31/12/2013)


Publications in cooperation with FAU scientists


Friedrich, O., Merten, A.-L., Schneidereit, D., Guo, Y., Schürmann, S., & Martinac, B. (2019). Stretch in Focus: 2D Inplane Cell Stretch Systems for Studies of Cardiac Mechano-Signaling. Frontiers in Bioengineering and Biotechnology, 7. https://dx.doi.org/10.3389/fbioe.2019.00055
Schürmann, S., Wagner, S., Herlitze, S., Fischer, C., Gumbrecht, S., Wirth-Hücking, A.,... Friedrich, O. (2016). The IsoStretcher: An isotropic cell stretch device to study mechanical biosensor pathways in living cells. Biosensors and Bioelectronics, 81, 363-72. https://dx.doi.org/10.1016/j.bios.2016.03.015
Paul, M., Harvey, R.P., Wegner, M., & Sock, E. (2014). Cardiac outflow tract development relies on the complex function of Sox4 and Sox11 in multiple cell types. Cellular and Molecular Life Sciences, 71(15), 2931-45. https://dx.doi.org/10.1007/s00018-013-1523-x
Nikolova-Krstevski, V., Wagner, S., Friedrich, O., & Fatkin, D. (2013, August). Transient Receptor Potential Channel 6 (TRPC6) Is An Important Mediator Of Mechanical Stretch Responses In The Atrial Endocardial Endothelium. Poster presentation.
Friedrich, O., Wagner, S., Battle, A., Schürmann, S., & Martinac, B. (2012). Mechano-regulation of the beating heart at the cellular level - Mechanosensitive channels in normal and diseased heart. Progress in Biophysics & Molecular Biology, 110(2-3), 226-238. https://dx.doi.org/10.1016/j.pbiomolbio.2012.08.009
Mohl, M.C., Iismaa, S.E., Xiao, X.-H., Friedrich, O., Wagner, S., Nikolova-Krstevski, V.,... Graham, R.M. (2011). Regulation of murine cardiac contractility by activation of α(1A)-adrenergic receptor-operated Ca(2+) entry. Cardiovascular research, 91(2), 310-9. https://dx.doi.org/10.1093/cvr/cvr081
Teichmann, M.D.H., von Wegner, F., Fink, R., Chamberlain, J.S., Launikonis, B.S., Martinac, B., & Friedrich, O. (2008). Inhibitory control over Ca(2+) sparks via mechanosensitive channels is disrupted in dystrophin deficient muscle but restored by mini-dystrophin expression. PLoS ONE, 3(11), e3644. https://dx.doi.org/10.1371/journal.pone.0003644

Last updated on 2015-10-12 at 14:37