Heinz Maier-Leibnitz Prize
Award year: 2016
Category: Award / Honour
Type: Heinz Maier-Leibnitz Prize
Awarding organization: Deutsche Forschungsgemeinschaft (DFG)
During her research, Aline Bozec discovered that there are various interfaces between bones and other tissue and organ systems. In her work she has described the central transcription factors and signalling pathways that are relevant to the differentiation and activity of cells in osteoclasts (cells that break down bone), osteoblasts (cells that build bone), and fat cells. In doing so she has shed light on fundamental phenomena relating to the regulation of bone formation and resorption, the modulation of regenerative mechanisms in stem cells niches in bone marrow, and how these processes affect health and disease.